
Source:
On the command line in AutoCAD, type CURSORTYPE and set it to 1. On the command line in AutoCAD, type GRAPHICSCONFIG and turn off hardware acceleration.
Source:
https://blogs.rand.com/support/2013/08/why-is-my-cursor-very-slow-or-jumpy-in-autocad.html
I found this worked in AutoCAD 2011: disable the tooltips - ROLLOVERTIPS=0.